Notice of Special Interest: Ending the HIV Epidemic

NIAID, along with several other Institutes and Centers (ICs), has issued a Notice of Special Interest (NOSI): Ending the HIV Epidemic, which solicits implementation science projects to advance the goals of the Ending the HIV Epidemic in the US (EHE) Initiative. The Initiative, launched in 2019, is a bold plan developed by agencies across the Department of Health and Human Services (HHS) to substantially reduce new HIV infections in communities disproportionately impacted by HIV.

Awarded projects responsive to this NOSI will have the opportunity to become part of a national network of HIV implementation science researchers, with access to resources and support from the NIH-funded Coordination, Consultation and Data Management Center (CCDMC) and Regional Implementation Science Hubs. Awardees will maximize the public health impact of their projects by working with the CCDMC to report and disseminate study progress and outcomes. In addition to networking with other researchers, awardees will also have opportunities to engage with federal staff across HHS as they contribute to this important national initiative.

Applications to this NOSI must be grounded in implementation science, and address one or more of the four strategies outlined in the EHE initiative:

    • Diagnose all people with HIV as early as possible
    • Treat people with HIV rapidly and effectively to reach sustained viral suppression
    • Prevent new HIV transmissions by using proven interventions, including pre-exposure prophylaxis (PrEP) and syringe services programs
    • Respond quickly to potential HIV outbreaks to get needed prevention and treatment services to people who need them

Applications must also focus on one or more of the 57 EHE geographic priority areas. Projects should support local EHE efforts through meaningful engagement with implementing partners such as public health departments, healthcare organizations, and other service providers, as well as community members and people with lived experience. Interested applicants should refer to the full NOSI for a complete list of requirements.

This notice applies to due dates on or after September 7, 2024, and subsequent receipt dates through January 9, 2026.

How to Get Started

ISCI offers numerous resources to help you in submitting your grant application, which includes but is not limited to the following:

    • Implementation Outcomes Crosswalk: A tool that guides implementation partners in identifying and selecting relevant implementation outcomes for their implementation research projects
    • Implementation Research Logic Model: An organizing tool that improves the specification, rigor, reproducibility, and transparency of implementation research projects of various study designs and at various stages of research
    • Literature Review Dashboard: An interactive database tool comprised of hundreds of US studies that identify multilevel determinants of HIV implementation, which can inform delivery of HIV programs and services
    • Resources Page: A variety of implementation science and HIV resources that can be relevant to your applications, including third party tools, websites, relevant papers, and videos