Ending the HIV Epidemic Projects
Ending the HIV Epidemic Projects
About Ending the HIV Epidemic Projects
Since 2019, the National Institutes of Health (NIH) has provided awards to institutions participating in the NIH-funded Centers for AIDS Research (CFAR) and the NIMH AIDS Research Centers (ARC) programs. We refer to these as Ending the HIV Epidemic (EHE) projects. These projects support research in 33 priority counties; Washington, DC; and San Juan Municipio (Puerto Rico).
With the coordination and help of the HIV Implementation Science Coordination Initiative (ISCI), the projects strengthen research-community collaborations and enhance the implementation science knowledge base needed for the EHE initiative. The projects involve partnerships between CFAR/ARC investigators, local health officials, and community groups in EHE priority areas.
Key Findings from EHE Projects
The NIH has funded over 200 collaborative projects between academic centers for AIDS research and HIV service providers (health departments, health systems, community orgs). ISCI has collected information covering project activities, accomplishments, and more. More information will be published as it is made available.
Real-World Application: Project Spotlight Article Series
Learn more about EHE project development, implementation, and findings by reading articles in our EHE Supplement Project Spotlight series. The series provides valuable insight into how researchers, providers, and community members scale up HIV prevention and treatment strategies. Each article focuses on the implementation of one EHE project and includes resources such as implementation strategies, trainings, marketing materials, and more.
Nation-Wide EHE Project Findings and Next Steps
ISCI researchers developed and organized supplemental issues of the Journal of Acquired Immune Deficiency Syndromes (JAIDS) in July 2022 and April 2025. The issues collectively highlight findings from the 2019-2024 EHE projects, which includes all geographic regions of the United States, a wide range of priority populations, and the four pillars of the EHE initiative (Prevent, Treat, Diagnose, and Respond).
2022 JAIDS Supplemental Issue
“Harmonizing Implementation Science to Inform Strategies for Ending the HIV Epidemic in the United States”
Volume 90, supplement 1
2025 JAIDS Supplemental Issue
“State of US HIV Implementation Science: Progress and Priorities to End the Epidemic by 2030”
Volume 98, supplement 5
National Kickoff Video
In this video you will find a brief introduction from the NIH, ISCI, and the IS Hubs. Find out more about Hub PIs and staff, as well as what each Hub specializes in and how they can support your EHE project.